1.个人简历
李刚，重庆大学光电工程学院，教授，博士生导师。主要从事生物微机电系统（BioMEMS）和微流控技术方面的研究，研究内容包括BioMEMS工艺、器件和系统以及微流控技术及应用等，近年来研究重点聚焦于基于微流控技术的简易低成本微型诊疗设备、蛋白质结晶微系统和基于MEMS技术的神经-电子接口器件等三方面。自2005年以来，先后主持和参与了国家973计划课题2项、863目标导向项目子课题1项、863前沿探索项目 1项、中科院科研装备研制项目 2项、国家自然科学基金面上项目 3项、上海市科委项目4项、重庆市科委项目2项，项目总经费近二千万元。至今共发表研究论文100余篇（其中SCI 一区14篇）， 申请发明专利52项（其中授权35项），参编教材一部、专著一部。
2. 教育及工作经历
教育经历
2005/5-2008/6，中国科学院大学，微电子学与固体电子学专业，工学博士
2000/9-2003/7，清华大学，生物物理专业，理学硕士
1988/9-1992/7，南开大学，生物物理专业，理学学士
工作经历
2015/3--至今 重庆大学，光电工程学院，特聘教授，博士生导师
2003/7-2015/2 中国科学院上海微系统与信息技术研究所，传感技术联合国家重点实验室，先后任助理研究员、副研究员、研究员
1998/8-2000/8 武汉大学医学部（原湖北医科大学）,医学物理教研室，先后任助教，讲师
3. 研究方向
（1）简易低成本微流控技术及应用
（2）基于微流控技术的结晶微系统
（3）基于MEMS技术的柔性可穿戴传感器件
4. 主要学术贡献（研究成果）
(1) 基于MEMS技术的柔性神经-电子接口器件。探索建立了一系列基于聚合物材料的植入式柔性神经微电极制作的成熟工艺，并研制成功了双面、金字塔形、半球形和集成纳米结构等多种形式的柔性神经微电极，为神经康复治疗和人工视觉假体的研究奠定了很好的基础。
(2) 基于微流控技术的蛋白质结晶微系统。成功研制多款基于微流控技术的高通量蛋白质结晶芯片，包括基于蒸发扩散模式的蛋白质结晶芯片、基于微批量模式的蛋白质结晶芯片和基于逆向扩散模式的蛋白质结晶芯片，这些芯片已在复旦大学生理学和生物物理学系等相关结构生物学实验室得到初步应用和认可，为结构生物学的研究和发展提供了一种很好的工具和平台。
(3) 简易低成本微流控技术。发展了多种基于无源模式的自动微量样品操控方法，包括基于毛细作用和离心力协同作用的高通量筛选技术、基于即贴即用型预脱气PDMS微泵和毛细微阀协同作用的自动定量分配和混合的技术以及基于油相触发的被动微阀技术，这些技术为发展简易、低成本、自动化的微型生化分析检测器件或设备，以应用于偏远乡村或社区诊所中疾病的快速、低成本诊断提供了很好的技术保障。
5.代表性的文章列表(*通讯作者)
(1) Gang Li*, Rui Ran, Jian-Long Zhao, Yuan-Sen Xu. Design, simulation and optimization of a miniaturized device for size-fractioned DNA extraction. Electrophoresis, 2007, 28(24): 4661–4667.
(2) Gang Li*, Qiang Chen, Junjun Li, Xiaojian Hu, Jianlong Zhao. A compact disk-like centrifugal microfluidic system for high-throughput nanoliter-scale protein crystallization screening. Analytical Chemistry, 2010, 82 (11):4362–4369.
(3)Gang Li*, Yahui Luo, Qiang Chen, Lingying Liao, and Jianlong Zhao. A "place n play" modular pump for portable microfluidic applications. Biomicrofluidics, 2012, 6(1): 014118.
(4)Kunpeng Gao, Gang Li*, Lingying Liao, Ji Cheng, Jianlong Zhao, Yuansen Xu. Fabrication of flexible microelectrode arrays integrated with microfluidic channels for stable neural interfaces. Sensors and Actuators A: Physical, 2013, 197(1):9-14.
(5)Honglian Zhang, Gang Li*, Lingying Liao, HongJu Mao, Qinghui Jin*, Jianlong Zhao*. Direct detection of cancer biomarkers in blood using a “place n play” modular polydimethylsiloxane pump. Biomicrofluidics, 2013, 7(3):034105.
(6)Qiang Chen, Gang Li*, Yuan Nie, Shuhuai Yao, Jianlong Zhao*. Investigation and improvement of reversible microfluidic devices based on glass-PDMS-glass sandwich configuration. Microfluidics and Nanofluidics, 2014, 16(1-2): 83-90.
(7)Ting Huang, Chun-Ping Jia, Jun-Yang, Wen-Jie Sun, Wen-Tao Wang, Hong-Lian Zhang, Hui Cong, Feng-Xiang Jing, Hong-Ju Mao, Qing-Hui Jin, Zhen Zhang, Jie-Ying Chen, Gang Li*, Guo-Xin Mao,* Jian-Long Zhao. Highly sensitive enumeration of circulating tumor cells in lung cancer patients using a size-based filtration microfluidic chip. Biosensors and Bioelectronics, 2014, 51:213–218.
(8)Hongbo Zhou, Yuan Yao, Qiang Chen, Gang Li, and Shuhuai Yao*. A facile microfluidic strategy for measuring interfacial tension. Applied Physics Letter, 2013, 103(23):234102.
(9)Hongbo Zhou, Gang Li, and Shuhuai Yao*. A droplet-based pH regulator in microfluidics. Lab on a Chip, 2014, 14(11):1917-1922.
(10)Teng Tang, Gang Li*, Chunping Jia, Kunpeng Gao, Jianlong Zhao*. An equipment-free PDMS Microfluidic Spotter for Fabrication of Microarrays. Biomicrofluidics, 2014, 8(2):026501.
(11)Xiaoyun Fan, Chunping Jia*, Jun Yang, Gang Li*, Hongju Mao, Qinghui Jin, Jianlong Zhao. A Microfluidic Chip Integrated with a High-Density PDMS Microfiltration Membrane for Rapid Isolation and Detection of Circulating Tumor Cells. Biosensors and Bioelectronics, 2015, 71:380–386.
(12)Li Wang, Kailei Sun, Xiaojian Hu*, Gang Li*, Qinghui Jin and Jianlong Zhao. A Centrifugal Microfluidic Device for Screening Protein Crystallization Conditions by Vapor Diffusion. Sensors & Actuators: B. Chemical, 2015, 219:105–111.
(13)Kunpeng Gao, Zhuanghui Zhu, Jinyi Yan, Lingying Liao, Ji Cheng, Gang Li*, Qinghui Jin, Jianlong Zhao. Fabrication of carbon nanowire arrays using inhomogeneous dissolution-diffusion kinetics and photoresist pyrolysis. Journal of Nanoscience and Nanotechnology, 2015, 15:6621-6627.
(14)Xiaojun Bian, Fengxiang Jing, Gang Li, Xiaoyun Fan, Hongbo Zhou, Qinghui Jin*, Jianlong Zhao*. A microfluidic droplet digital PCR for simultaneous detection of pathogenic Escherichia coli O157 and Listeria monocytogenes. Biosensors and Bioelectronics, 2015, 74:770–777.
(15)Xiang Li, Zeta Tak For Yu, Dalton Geraldo, Shinuo Weng, Nitesh Alve, Wu Dun, Akshay Kini, Karan Patel, Roberto Shu, Feng Zhang, Gang Li, qinghui Jin, Jianping Fu. Desktop aligner for fabrication of multilayer microfluidic devices. Review of Scientific Instruments, 2015, 86(7):075008.
(16) Ping Wang, Fengxiang Jing, Gang Li, Zhenhua Wu, Zule Cheng, Jishen Zhang, Honglian Zhang, Chunping Jia, Qinghui Jin, Hongju Mao, Jianlong Zhao. Absolute quantification of lung cancer related microRNA by droplet digital PCR. Biosensors and Bioelectronics, 2015, 74:836-842.
(17)Lifen Liu, Simin Wu, Fengxiang Jing, Hongbo Zhou, Chunping Jia, Gang Li, Hui Cong , Qinghui Jin, Jianlong Zhao. Bead-based microarray immunoassay for lung cancer biomarkers using quantum dots as labels. Biosensors and Bioelectronics, 2016, 80:300-306.
(18) Yayun Fu, Hongbo Zhou, Chunping Jia, Fengxiang Jing , Qinghui Jin, Jianlong Zhao, Gang Li*. A microfluidic chip based on surfactant-doped polydimethylsiloxane (PDMS) in a sandwich configuration for low-cost and robust digital PCR. Sensors and Actuators B: Chemical, 2017, 245:414–422.
(19)Zhenhua Wu, Yanan Bai, Zule Cheng, Fangming Liu, Ping Wang, Dawei Yang, Gang Li, Qinghui Jin, Hongju Mao, Jianlong Zhao. Absolute quantification of DNA methylation using microfluidic chip-based digital PCR. Biosensors and Bioelectronics, 2017, 96:339–344.
(20) Chao Yang, Yongfeng Ning, Xiaoyong Ku, Guisheng Zhuang, Gang Li*. Automatic Magnetic Manipulation of Droplets on an Open Surface Using a Superhydrophobic Electromagnet Needle. Sensors and Actuators B: Chemical, 2018, 257: 409-418.
(21)Chao Yang, Gang Li*. A novel magnet-actuated droplet manipulation platform using a floating ferrofluid film. Scientific Reports, 2017, 7: 15705.
(22) Ling Zhou, Guisheng Zhuang and Gang Li*. A Facile method for the fabrication of glass-PDMS-glass sandwich microfluidic devices by sacrificial molding. Sensors and Actuators B: Chemical, 2018, 261:364-371.
(23)Xiaoyong Ku, Guisheng Zhuang, and Gang Li*. A universal approach for irreversible bonding of rigid substrate-based microfluidic devices at room temperature. Microfluidics and Nanofluidics, 2018, 22:17.
(24) Chao Yang, Zongwei Zhang, and Gang Li*. Programmable droplet manipulation by combining a superhydrophobic magnetic film and an electromagnetic pillar array. Sensors and Actuators B: Chemical, 2018, 262: 892–901.
(25)Chao Yang, Lei Wu, and Gang Li*. Magnetically Responsive Superhydrophobic Surface: In Situ Reversible Switching of Water Droplet Wettability and Adhesion for Droplet Manipulation. ACS Applied Materials & Interfaces, 2018, 10 (23):20150–20158
联系方式：
地 址：重庆市沙坪坝区沙正街174号重庆大学A区微系统中心304室
E-mail： gang_li@cqu.edu.cn
